It is often used instead of n-butanol as a solvent for coatings and pharmaceuticals.It is used as an internal combustion engine fuel additive (to prevent carburetor icing) and an antiknock agent.As an intermediate in organic synthesis and an alkylation raw material for the production of tert-butyl compounds, it can be used to produce methyl methacrylate, tert-butylamine, etc., which are applied in the synthesis of medicines and fragrances.Dehydration of tert-butanol can produce isobutylene with a purity of 99.0–99.9%.It is used as a solvent for industrial detergents, a pharmaceutical extractant, an insecticide, a solvent for waxes, and a solvent for cellulose esters, plastics and paints.It is also used in the manufacture of denatured alcohol, fragrances, fruit essences, isobutylene, etc.It serves as a solvent for molecular weight determination and a reference substance for chromatographic analysis.