Colorless transparent fuming liquid with a strong pungent odor. It is chemically reactive and a highly efficient acylating agent, with stronger acylating ability than acetic anhydride. It reacts violently with polar substances such as water and alcohols, releasing hydrogen chloride gas and generating a large amount of heat.
Physical & Chemical Properties
Molecular FormulaCH3COCl
Density:1.11g/cm³g/cm³
Boiling Point:51℃
Solubility:
It is miscible with acetone, chloroform, glacial acetic acid, petroleum ether, diethyl ether and benzene. It decomposes violently in contact with water; contact with water is strictly prohibited.
Molecular Weight:78.5g/mol
Flash Point:5℃
Melting Point:-112℃
Uses
1. Key intermediate in organic synthesis: Used for the acylation of alcohols, phenols and amines to prepare esters, amides and other compounds.
2. Pharmaceutical field: Synthesis of various pharmaceutical raw materials (such as paracetamol, etc.).
3. Pesticide field: Preparation of pesticide intermediates for the synthesis of high-efficiency pesticides.
4. Dyes and fragrances field: Used in the synthesis of dye and fragrance intermediates.
5. Others: Catalyst for carboxylic acid chlorination; reagent for quantitative analysis of hydroxyl and amino groups.
Safety, Security & Risk
Physical Hazards
Vapors are heavier than air and may flow along the ground, causing ignition at a distance.
Chemical Hazards
When heated or burned, it decomposes to generate toxic and corrosive fumes containing hydrogen chloride and phosgene.Reacts with moisture in the air to form fumes of hydrochloric acid and acetic acid.Risk of poisoning.Reacts violently with water, alcohols, acids, alkalis, certain powdered metals and many other compounds.Risk of fire and explosion.Corrodes many metals in the presence of water.