White to almost white crystalline powder, odorless or slightly odorous, with acidic taste. It has stable physicochemical properties and is one of the 13 essential vitamins for humans.When administered at high doses, it can effectively reduce low-density lipoprotein (LDL) cholesterol and increase high-density lipoprotein (HDL) cholesterol, thus giving this drug unique value in the treatment of dyslipidemia.Nicotinic acid may cause mild to moderate elevations in serum transaminase at high doses, and certain nicotinic acid preparations have been associated with clinically apparent acute liver injury, which can be severe or even fatal.
Physical & Chemical Properties
Molecular FormulaC6H5NO2
Density:1.5g/cm³g/cm³
Boiling Point:
Solubility:
Soluble in water, freely soluble in boiling water, soluble in ethanol, practically insoluble in ether and chloroform.
Molecular Weight:123.1g/mol
Flash Point:193℃
Melting Point:236.6℃
Uses
1. Food additive: Nutritional fortifier, used in rice and flour products, infant food, and health products.
2. Pharmaceutical raw material: For the preparation of nicotinic acid tablets and nicotinamide, used in the treatment of pellagra and hyperlipidemia.
3. Feed additive: Nutritional supplement for livestock and poultry, promoting growth and improving meat quality.
4. Chemical intermediate: For the synthesis of nicotinamide, dyes and other pyridine derivatives.
Safety, Security & Risk
Physical Hazards
As a powder or granule, it may form an explosive dust-air mixture.
Chemical Hazards
Combustion produces toxic gases containing nitrogen oxides.Reacts with oxidizing agents, strong acids and alkalis.